Maccabitech
Clinical Database Research
Contact Us +972-3-514-3755

Pharma / CROs / Biotech

VALUE PROPOSITION

Accelerate pharmaceutical product development – reducing costs and enhancing revenues through faster time to market
Identification of new indications for existing pharmaceutical products – creating additional IP related revenues (drug re-profiling)
Early identification of unanticipated side effects and adverse reactions
Rapid identification and assembly of physician and patient cohorts for prospective studies
Pre-selection and feasibility studies – reducing the time for patient recruitment for clinical trials
Ability to test hypotheses related to performance of new technologies vs. existing treatment protocols – supporting the R&D process

OUR SERVICES

Burden-­of-­disease and cost-­effectiveness studies

Maccabi's database research service can perform studies to help understand the cost burden of disease within a population, including hospitalizations, use of diagnostic services, drugs and days lost from work. Similarly, we are able to compare the cost and burden of various treatments, disease management programs and other interventions.

Related Publications

Potential impact and cost-­effectiveness analysis of rotavirus vaccination of children in Israel

Chodick G, Waisbourd-­Zinman O, Shalev V, Kokia E, Rabinovich M, Ashkenazi S
European Journal of Public Health 2009;19 :254-­9.  
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Post-­marketing surveillance of recently introduced products and technologies

Outcomes research
Phase IV studies
Comparative effectiveness
Pharmacoepidemiological studies
Compliance
Pharmaceutical effectiveness, side effects
Patient safety studies
Quality of life studies
Using its database, Maccabi's database research service can help clients understand the impact of their products on the population. The effectiveness of treatments can be compared, side effects tracked and measured. Because Maccabi's database includes complete drug purchase records, not merely the prescriptions, we can study and evaluate drug compliance. Because of our ability to interact directly with the physicians, we can evaluate quality of life, in addition to other outcomes. Our survey research department has expertise in conducting follow-up surveys directly with patients to supplement the information available in our database.
Related Publications

Long-Term Persistence with Statin Therapy in a Non-For-Profit Health Maintenance Organization: A Population-Based Retrospective Cohort Study

Chodick G, Shalev V, Gerber Y, Heymann AD, Silber H, Simah V, Kokia E.
Clinical Therapeutics 2008;30:2167-2179

Hepatotoxicity rates do not differ in patients with rheumatoid arthritis and psoriasis treated with methotrexate

Amital H, Arnson Y, Chodick G, Shalev V.
Rheumatology (Oxford). 2009;48:1107-10
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Comparative Effectiveness and Outcomes Research

pharmacoepidemiological studies
drug compliance
pharmaceutical effectiveness, side effects
patient safety studies
quality of life studies
Using its database, Maccabi's database research service can help clients understand the impact of treatments on patients. The effectiveness of various approaches can be compared, side effects tracked and measured. Because Maccabi's database includes complete drug purchase records, not merely the prescriptions, we can study and evaluate drug compliance. Because of our ability to interact directly with the physicians, we can evaluate quality of life, in addition to other outcomes.
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Epidemiological investigations

Prevalence studies
Disease and treatment related research
Observational studies conducted on selected populations
Related Publications

Diabetes and Risk of Incident Cancer: A Large Population-Based Cohort Study in Israel .

Chodick G, Heymann AD, , Kokia E, Shalev V.
Cancer Causes Control, 2010; 21(6):879-87

Long-term trends in hepatitis A incidence following the inclusion of Hepatitis A vaccine in the routine nationwide immunization program

Chodick G, Heymann AD, Ashkenazi S, Kokia E, Shalev V.
Journal of Viral Hepatitis 2008; Sup2:62
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Survey research

Maccabi database research service includes a staff of expert survey researchers, who can develop and conduct online, telephone and paper surveys independently or as an adjunct to other Maccabi research services.
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